Jim, a sexy icon of the Parisian gay scene, sees his life turned upside down when he contracts Hétérose, a strange virus that transforms gay men... into heterosexuals! He then finds everyone turning their backs on him, except for his latest follower (and first admirer), Lucien, a young man who struggles to accept himself. Together, they set off in search of a mysterious remedy capable of curing Jim and preventing the extinction of homosexuality...